Differential Effects Of Two Different Isoenergetic Meals One Rich In Saturated And One Rich In Monounsaturated Fat On Endothelial Function In Subjects With Type 2 Diabetes Mellitus, Diabetes Care, December 2008
After 33 participants with type 2 diabetes consumed either a meal high in saturated fat (butter), or high in monounsaturated fat (olive oil), (meals had the same number of calories) their artery function was assessed.
Flow-mediated dilation (FMD):
- Declined by 16.7% after the saturated-fat-rich meal
- Increased by 5.2% after the monounsaturated-fat-rich meal
The authors concluded:
"Consumption of an SAFA-rich meal is harmful for the endothelium, while a MUFA-rich meal does not impair endothelial function in subjects with type 2 diabetes."